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2.3 The synergistic network of microbial metabolites: integrating short-chain fatty acids and tryptophan derivatives 2.3.1 Short-chain fatty acids and their immunomodulatory effects The impact of the gut microbiota on host physiology is mediated by a complex network of metabolites, among which short-chain fatty acids (SCFAs) and tryptophan-derived indoles represent two pivotal communicative channels

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