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I wrote a bit about this on the HUL&ITC forums some are replicated here along with updated numbers

Alterations in the composition of the gut microbiome, a condition known as gut dysbiosis, have been strongly associated with a range of diseases, including inflammatory bowel disease (IBD), metabolic syndrome, and various cancers

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Research data on the tobacco industry, including statistics on sales, taxes, and consumption trends, can be found through ATCCs reports , as well as national sources like the Centers for Disease Control and Prevention (CDC) and the Tobacco Control Legal Consortium