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This principle of ICD can be confirmed by a vaccination scenario known as the gold standard vaccination assay, where inoculation of mice with tumor cells killed by ICD induction prevents the subsequent growth of live tumor cells ( + T cells within the tumor ( Evolution of ICD in cancer Various types of cell death, such as apoptosis, necrosis, alkaliptosis, anoikis, autosis, autophagy, cuproptosis, disulfidptosis, entosis, erebosis, ferroptosis, lysosomal cell death (LCD), methuosis, mitoptosis, necroptosis, NETosis, oxeiptosis, paraptosis, parthanatos, pyroptosis, and immunogenic cell death (ICD), have been identified, exhibiting either caspase-dependent or -independent characteristics