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Reference profile correlation reveals estrogen-like trancriptional activity of curcumin

Discussion Here, we identified three major inflammatory areas in our inflammation model based on the macrophage polarization and their cellular neighborhoods, whereby an inflammatory core region including the pathogen is surrounded by a proinflammatory region containing M1like macrophages and an outer region containing antiinflammatory cells

Theranostics 11 , 222 (2021)

The combination of improved sleep and reduced pain perception could create a virtuous cycle for those dealing with chronic pain conditions, where poor sleep and pain often reinforce each other