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Description

Slices were cultured in Minimum Essential Medium (MEM) with Hanks balanced salts [Thermo Fisher Scientific, #11575032], 1% penicillinstreptomycin and 25% horse serum [Thermo Fisher Scientific, #16050130] for 3 days, with 1 mL of medium added below the membrane insert

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Upon reaching the liver, these toxic compounds can overwhelm phase I and phase II detoxification pathways (174)

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