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These free radicals, generated as byproducts of normal metabolic processes or introduced through external factors like pollution and UV radiation, can damage cells and contribute to various skin and health issues

Originally, BPC 157 appears as a cytoprotective antiulcer peptide, stable in human gastric juice, previously employed in ulcerative colitis clinical trials and now in those concerning multiple sclerosis (Sikiric et al., 1993

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To modify antioxidants in therapy, strategies include targeting GPX4 activity, manipulating GSH levels, optimizing exogenous antioxidants, and exploiting Nuclear factor erythroid 2related factor 2 (NRF2) pathways [254]