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Discussion Our study establishes that non-gene-edited hCiPSC-NSCs, delivered via a dual-pathway strategy (intravenous systemic + intracerebroventricular boost), concurrently ameliorate ASD-like phenotypes in VPA-exposed rats by targeting the gut-brain axis

Similar to what we report for miR-4488, some rRFs are produced in a Drosha-independent but Dicer-dependent manner, whereas others are produced in a Dicer-independent manner (Rosace et al, 2020)