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All tissue biopsies were placed in a drying chamber until a stable weight was measured for approximately 48 hours

In addition, researchers have reported several agents able to inhibit the activity of ACSL4, such as triacsin C, thiazolidinediones (TZDs), abemaciclib, PRGL493, and valnoctamide

What they found: Favorable safety profile , no serious adverse events at doses up to 100 g/kg Preliminary efficacy signals positive The program stopped before Phase 3 for unknown commercial reasons (the program passed through several sponsor rotations and no one ultimately carried it through) Why it matters: These are the only published clinical data in humans that we have

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