is inducing glutathione pro-oxidant maintenance mitigates age-related susceptibility to redox cycling agents Apoptosis and glutathione: beyond an

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To survive under conditions of increased oxidative stress, cancer cells adopt various strategies to produce antioxidants, for example, upregulation of SLC7A11

All TrxR enzymes require an NADPH-dependent reduction step to exert their function in vivo and TrxR is a therapeutic target for cancer and infectious diseases 21,67

Intercellular transport of iron predominantly relies on the Tf/TfR1 system, while ferritin serves as the principal intracellular reservoir and buffer against labile iron fluctuations (Jain et al., 2023