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Death-associated protein kinase 1 (DAPK1) signaling pathway DAPK1 is a Ca 2+ /calmodulin-dependent serine/threonine-protein kinase, whose phosphorylation contributes to apoptotic cell death

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showed that L-glu release from astrocytes can activate so-called slow inward currents via extrasynaptic NMDAR receptors in CA1 neurons which thereby can be synchronized (Angulo et al., Different mechanisms through which astrocytes can release L-glu have been proposed: vesicular L-glu release (Adak et al., 2013) and connexin hemichannels (Stehberg et al., 2012) as well as release via the cystine/glutamate antiporter system x (Massie et al., 2015)