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Conclusion: Innate and adaptive immune cells have distinct distribution profiles in the salivary gland tissues of patients with pSS and are associated with different mitochondrial metabolic pathways, which may contribute to disease progression

In hairless skin model, the extract of Reynoutria multiflora could up regulate SOD in a dose-dependent manner, thereby reducing UVB-induced oxidative damage, suggesting that the extract of Reynoutria multiflora contains anti skin photoaging agent (Hwang et al., 2006)

At the same time, hepcidin levels increase, thereby accelerating the degradation of FPN, closing the iron transport outlet to the blood, and reducing the transport of iron from small intestinal epithelial cells and macrophages to the blood ( In addition, ferroptosis is closely related to iron metabolism under iron overload

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