glutathione with electrophile General scheme of (GSH) conjugation to a generic disulfide reductase Metabolism
Metabolism Bioactivation and Tissue Toxicity Biotransformation of Drugs B furosemide loop diuretic is metabolized by cyp4so to Fluorovinylsulfonamide as a Highly Reactivity and Structure Tunable Electrophile for Covalent Targeting of Proteins Journal of the American Chemical Society
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