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et al., The Swedish Snus and the Sudanese Toombak: Are They Different?, Oral Oncology

Pyrilamine is reported to be taken up from carrier-mediated transport with the involvement of H+/organic cation antiporter that drives H+ outward for its uptake, similar to that of nicotine, suggesting both molecules share a similar transport system for its uptake into the brain endothelial cells (Okura et al., 2008)

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The increase in the combined risk of coronary heart disease, heart attack and stroke was similar to the risk among the subset of adults who had never used e-cigarettes but did use cannabis