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AC lowered the expression of inflammatory markers such as nitrotyrosine, iNOS, poly (ADP-ribose), TNF-, and IL-1

Figure 7 The treatment of primary CLL lymphocytes with CB-839 alone increased mitochondrial superoxide production in both unstimulated (n = 15) and stimulated (n = 19) conditions (P = 0.006 and P = 0.02, respectively

doi: 10.3389/fnut.2025.1686056 Received 14 August 2025 Accepted 25 September 2025 Published 16 October 2025 Volume 12 - 2025 Edited by Mingyue Song, South China Agricultural University, China Reviewed by Ludovica Verde, University of Naples Federico II, Italy Arely Vergara-Castaeda, La Salle University of Northwest, Mexico Updates Copyright 2025 Chyliska and Maciejczyk