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This ecosystem represents about 2% of our body weight (approximately 1.5 kg) [58]

Healthcare providers may recommend laboratory testing to identify specific deficiencies before starting supplementation, particularly for patients with reduced food intake or persistent gastrointestinal symptoms

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However, due to the lack of ACTH measurements, a dual-cosine function was used to characterize circadian fluctuations resulting in reduced physiologically interpretable parameters compared to using surge functions