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Most of the studies (12 of 14) measured puffing topography in controlled environments, where puffing behavior may or may not represent e-cigarette use behavior in the real world. Two observational studies characterized puffing topography of experienced e-cigarette users of first-generation devices in their naturalistic environments

Secker-Walker RH, Solomon LJ, Flynn BS, Skelly JM, Lepage SS, Goodwin GD, Mead PB: Smoking relapse prevention counseling during prenatal and early postnatal care

Haas-Lucie Stern endowed chair in Cardiology, professor of medicine at the University of California at San Francisco

Cigarette cards can be found in set locations around the map, though players can also earn a random card from a packet of premium cigarettes