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To investigate the role of GSS in male reproduction, we constructed Gss Flox/Flox mice by inserting two LoxP site to the left and right of exon 3 (Fig

Kassar-Duchossoy L, et al

However, as the development of multi-specific protein therapeutics becomes more widespread, the potential for immune complex formation and consequent immunogenicity must be considered, as the latter can lead to both loss of pharmacodynamic activity and safety concerns