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It was also observed that the decellularization process of the sciatic nerve might denature ECM proteins, as cell proliferation was more significant on pure collagen hydrogels compared to acellular sciatic nerve

When theres a decrease of NAD+ in the body, this negatively affects mitochondrial health because theyre not able to repair the damage as well

While these bacterial enzymes have been explored for the generation of natural product analogs or applications in biocatalysis, the broad utility of amide bond-forming enzymes in enzymatic combinatorial synthesis has not been fully realized because of unwanted cross-reactivities of the enzymes toward substrates and/or difficulties in finding partnering enzymes with comparable substrate promiscuity 56

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