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The purpose of this review is to provide a state-of-the-art interdisciplinary and translational approach to arterial stiffness, highlighting unique pathophysiological mechanisms (e.g., perivascular adipose tissue, extracellular vesicles), clinical relevance, and future directions

These factors are not only prevalent but often pivotal in determining disease progression and treatment response in human neurological populations

doi: 10.1016/j.neuroscience.2019.01.027, 181 SefianiA.HorvatD.PewklangT.ThompsonT.MoreyS.AbdelfattahA.et al

There are now three different forms of SOD found in mammalian cells including extracellular superoxide dismutase (EcSOD, SOD3), manganese superoxide dismutase (Mn-SOD, SOD2), and copperzinc superoxide dismutase (Cu,Zn-SOD, SOD1) [15]