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Lower RMSD values associated with high-affinity poses affirm the computational reliability in capturing near-native conformations, elucidating the molecular dynamics governing these interactions and highlighting essential binding sites and amino acids

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Borges G, Fong RY, Ensunsa JL, Kimball J, Medici V, Ottaviani JI, et al

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For example, activation of the IRE1-XBP1 pathway produces XBP1s, which participates in the adaptive regulation of ERS and indirectly influences necroptosis by regulating the expression of certain anti-apoptotic proteins (Wang S

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