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Adeno-associated virus-mediated gene transfer of tissue inhibitor of metalloproteinases-1 impairs neutrophil extracellular trap formation and ameliorates hepatic ischemia and reperfusion injury

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George LA, Monahan PE, Eyster ME, Sullivan SK, Ragni MV, Croteau SE, Rasko JEJ, Recht M, Samelson-Jones BJ, MacDougall A, Jaworski K, Noble R, Curran M, Kuranda K, Mingozzi F, Chang T, Reape KZ, Anguela XM, High KA

In addition, neuronal MCT2 plays a unique role in long-term memory consolidation, and its knockdown in mature neurons also impairs hippocampal neurogenesis, revealing that MCT2 function extends beyond metabolic support to the regulation of plasticity-related processes