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Whilst anaemia typically resolves with B12 replacement, neurological damage may be permanent if deficiency remains untreated for extended periods

The reason for this is that any Glyteine inside cells is immediately converted to glutathione

Nevertheless, ongoing surveillance and research are important to fully characterize long-term safety as use of this therapy expands

The above analyses show that BaP may induce a decrease in DNA methylation level accompanied by abnormal methylation patterns of some certain genes (Table 1), and the hypermethylation of tumor suppressor genes by Bap contributes to the occurrence and development of cancer