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Article: Seek and you shall find

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Cigarette smoke and histone posttranscriptional modifications Cigarette smoke and histone acetylation Previous studies reported that CS caused histone hyperacetylation in the lungs of both human smokers [29, 30], mouse models exposed to CS [31], and human bronchial epithelial (HBE) cells treated with cigarette smoke extract (CSE) in vitro [32]