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Complications of coeliac disease include adverse reproductive outcomes, kidney and liver disease, infections, other autoimmune disease, certain cancers and neurological and psychiatric disease, reflecting the multisystemic nature of the disease

The injection is given intramuscularly in the gluteal muscle (upper outer part of the buttocks) or in the deltoid muscle (upper outer muscle of the arm)

B12 is used to initially treat B12 deficiency and anaemia

Patients affected by methylmalonic aciduria show cognitive impairment, and in mice, MMA accumulation in the brain causes neuroinflammation and oxidative stress injury (34)