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However, the selection of appropriate model structures is often based on a trial-and-error approach (Richelle & Bogaerts, 2015)

Krischer et al

How both of these two enzymes determine substrate specificity or how their regulation takes place can provide insight for discrimination/identification of developmental and stress responses

Importantly, however, particle design governs risk: surface-displayed antigens or certain chemistries can raise immunogenicity and, in rare cases, provoke severe hypersensitivity (including anaphylaxis), whereas encapsulation strategies tend to blunt immediate antigen recognition and are therefore often safer in vivo (206, 208)