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gasseri prevented dexamethasone (DEX)-induced muscle atrophy by stimulating myogenesis and protein synthesis through activation of the IGF-1-PI3K/AKT/mTOR pathway, reducing protein breakdown via FOXO-mediated modulation of the ubiquitin-proteasome pathway (UPP) and autophagy lysosomal pathway (ALP)

DAMPs, PAMPs, NLRs, RIGs, CLRs and TLRs Understanding the alphabet soup in the context of bone biology

Furthermore, AgNPs may circumvent chemoresistance mechanisms, such as drug efflux or DNA repair upregulation, through multifaceted actions including ROS generation, mitochondrial dysfunction, and signaling pathway interference