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In lung cancer, triptolide enhances the efficacy of EGFR tyrosine kinase inhibitors such as gefitinib, erlotinib, and icotinib, which are standard targeted therapies for NSCLC with EGFR mutation cell carcinoma [988]

Wnt proteins guide the axons of the spinal cord in an anterior-posterior direction

High-throughput screening platforms, computational drug discovery approaches, and structure-activity relationship studies should be employed to optimize the specificity and potency of these agents

This is great news, especially when we consider that drug overdose is the leading cause of death among Americans under the age of 50, 1 and that opioids drugs like oxycodone, hydrocodone, morphine, heroin, codeine, and fentanyl are implicated in overdose deaths more than any other drug class, ending more lives than guns, breast cancer, or car accidents