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The cymba concha and inner ear were considered to be the best locations for stimulation of the auditory vagus nerve (Butt et al., 2020), while the carotid bifurcation was the most effective area, so further determination of the location of taVNS stimulation is needed

Second, to ensure independence among genetic variants, we conducted linkage disequilibrium (LD) clumping using PLINK with a 10,000 kb window and an r threshold of 0.001, referencing the European population from the 1000 Genomes Project

Engebretson S, Kocher T (2013) Evidence that periodontal treatment improves diabetes outcomes: A systematic review and meta-analysis

This suggestion was further insisted as a potential mechanism of TB-500 by the authors of the research study, who also commented that " transfection of anti-miR-146a nucleotides reversed the inhibitory effect of T4 on IRAK1 and TRAF6