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This surge may be partly attributable to efforts by the tobacco industry, which has actively advocated for state laws prohibiting sales to minors

Nonetheless, the anonymised data on which this manuscript was based could be made available to other investigators upon bona fide request and following all the necessary approvals (including ethics approval) of the detailed study proposal and statistical analyses plan

Genetic manipulation of CIA, using DR4 and DQ8 human transgenic mice, have also been investigated for their contribution to murine arthritis using a modified protocol (20)

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