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In mouse embryonic fibroblasts, the elevation of CHAC1 protein expression following As III exposure is negatively regulated by the Tribbles homolog 3 (TRIB3), which limits CHAC1s pro-death potential (rd et al., 2016)

10.1371/journal.pone.0080397 189 YehS

Ferroptosis Plays a Crucial Role in Papillary Thyroid Carcinoma and FTO Regulates PTC Cell Ferroptosis by Mediating the m6A Methylation of SLC7A11 The latest research demonstrates that SLC7A11 can enhance tumor development by inhibiting ferroptosis and other ferroptosis-independent functions [31]