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In vivo , a compromised astroglial glutathione system may contribute to a lower defense capacity of the brain against ROS and subsequently to increased susceptibility to ROS of astrocytes themselves and of neighboring cells ( The Role of Glutathione Peroxidase 4 in Blood-Brain Barrier Glutathione peroxidase 4, a GSH-dependent enzyme downstream of the system, assists to maintain membrane fluidity by reducing lipid peroxides

Oxidative stress markersincluding F2-isoprostanes, 8-oxo-dG, and malondialdehydereflect whether your cells are experiencing excess free-radical burden

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