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TDP-43 SUMOylation at K408 supports cellular stress response and recovery in neurons As TDP-43 SUMOylation responds to, and is cleared during cellular stress and recovery respectively, we posited that SUMOylated TDP-43 plays key roles in responding and recovering from stress

58 LiC.ZhangY.LiuJ.KangR.KlionskyD.TangD

The five inhibitors considered in the present investigation are thiamine (vitamin B1 ), pantothenic acid (vitamin B5 ), pyridoxine (vitamin B6 ), Biotin (vitamin B7 ), -tocopherol (vitamin E ), and glutathione ( GSH ), their 2D structures are shown in Fig

The molecular core of this pathway, elucidated over the last decade, consists of RCAR/PYR1/PYL receptors, PP2C phosphatases, and SnRK2 kinases (Fujii et al