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Like cigarette smokers, shisha smokers are at risk of developing heart and circulatory diseases, cancers, respiratory diseases, nicotine addiction, and problems during pregnancy

Although plants typically eliminate excess ROS through their antioxidant system, under the chilling stress in this study, the activities of key antioxidant enzymes such as SOD and POD were significantly reduced, with only CAT activated in an attempt to remove the excess ROS ( 4.2 Metabolomics analysis of tobacco field chilling injury Changes at the physiological level are often accompanied by the reorganization of metabolic networks to enhance the plants resistance to stress