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Clara cells are an important source of antioxidant/detoxification gene expression in response to cigarette smoke exposure via the Nrf2 transcription factor

While they have different functions, both L-carnitine and L-carnosine are naturally occurring compounds found in the human body

Clinical manifestations may involve multiple systems, including neurological, gastrointestinal, and musculoskeletal domains

Complementing these effects, KPV exerts tissue-selective anti-inflammatory activity by inhibiting NF-B signaling, reducing adhesion molecule expression, and suppressing pro-inflammatory cytokines, thereby maintaining a controlled immune environment conducive to repair