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Advanced Synthesis & Catalysis 361(11):25142525

The most important things are free, Marcus says

Los estudios in vitro y en modelos animales han revelado que su mecanismo de accin no depende de un solo receptor, sino de una cascada de sealizacin intracelular compleja

Final results of a phase Ib dose-escalation study of PRI-724, a CBP/beta-catenin modulator, plus gemcitabine (GEM) in patients with advanced pancreatic adenocarcinoma (APC) as second-line therapy after FOLFIRINOX or FOLFOX