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In addition, a 2013 systematic review by the same investigators identified only two small randomized, double-blind, placebo-controlled trials that examined the effect of vitamin C on the incidence of respiratory infection-induced asthma (214)

Resveratrol was shown to decrease IL-1 and tumor necrosis factor-[105] expression and reduce iNOS expression, COX-2 messenger RNA, and production of IL-8 and GM-CSF[106] in human lung epithelial cells More studies need be done to understand how resveratrol fits into inflammatory pathways in the development of novel therapies for the treatment of asthma

Konstan MW, Geller DE, Mini P, Brockhaus F, Zhang J, Angyalosi G

Antifibrotic action of Cu/Zn SOD is mediated by TGF-1 repression and phenotypic reversion of myofibroblasts