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Although N-acetylcysteine (NAC) directly influences the pool of extracellular cystine and intracellular cysteine via a series of plasmatic redox reactions, in order to be effective, intracellular cysteine precursors must be designed to enter erythrocytes rapidly and use high activity enzymes within erythrocytes to liberate cysteine (Whillier et al., 2009

Marreiro DD, Cruz KJ, Morais JB, Beserra JB, Severo JS, de Oliveira AR

(2023) found that exogenous melatonin improved the germination rate and germination potential of melon seeds under different conditions by up-regulating the expression of amylase and some melatonin-synthesis genes as well as the activities of antioxidant enzymes and amylase, and reducing the content of malondialdehyde and reactive oxygen species

Consistently, bacterial GSTs have been implicated in antibiotic resistance phenotypes