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SCFAs such as butyrate can target the GPR41 and olfactory receptor 78 (Olfr78) to prevent programmed hypertension by regulating cAMP (102, 175)

The central and diverse functions of the thioredoxin system currently make it one of the most attractive targets for antitumour drug development 2,3

We further propose companion diagnostics that quantify sulfur/selenium species and enzyme activity to enable patient stratification and de-risk clinical translation