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89 Restoration of the ECM to is original state re-establishes homeostasis, whilst excessive deposition of connective tissue or inadequate remodeling can result in fibrosis

Lowering oxygen levels to 5%, 1% and 0.1% for 6 h before re-oxygenation to ambient levels confirmed fast and reversible NAD reduction in Arabidopsis leaf tissue at 1 and 0.1% oxygen ( Figure 4FJ and Figure S9 )

Of the 50 markers investigated, 4, 11 and 25 serum and plasma analytes were significantly different from controls in mild, moderate and severe groups, respectively after false discovery rate (FDR) correction and included several well-defined pro-inflammatory cytokines, including interferon- (IFN), interleukin-6 (IL-6), interleukin-1 (IL-1), interleukin-1RA (IL-1RA), interleukin-8 (IL-8) and 10 kDa interferon gamma-induced protein (IP-10)

Copper in cancer: from pathogenesis to therapy