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doi: 10.1002/cmdc.201500486 189 ShenY.TakahashiM.ByunH.-M.LinkA.SharmaN.BalaguerF.et al

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Impact of Cytogenetic Abnormalities and Cytogenetic Response to Hypomethylating Agents (HMAs) in Patients (pts) with Lower Risk Myelodysplastic Syndromes (MDS)

Pieper emphasized that currently available over-the-counter NAD+ precursors have been shown in animal models to raise cellular NAD+ to dangerously high levels that promote cancer. This conclusion extrapolates beyond the published findings and lacks support from human clinical evidence