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In this situation, it can be challenging to demonstrate B12 deficiency even when there are typical symptoms (including neuropathy-like paraesthesia and numbness), as serum B12 concentrations may be just within, or sometimes above, the normal range due to the oral supplementation

There is currently no clear evidence that vitamin B12 deficiency has an etiological role in frailty [54] or sarcopenia [57] in elderly people

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