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9 Emerging therapeutic interventions targeting metabolism and mitochondria 9.1 Metabolic modulators 9.1.1 Intranasal insulin Central nervous system (CNS) insulin deficiency may result from impaired insulin transport across the blood-brain barrier (BBB)

It is also involved in several metabolic and biochemical processes, such as DNA synthesis and repair, protein synthesis, and regulation of cell proliferation and apoptosis

That is, there is a link between redox potential, oxidative stress and human microbiota according to the oxygen tolerance of each species and the abundance of antioxidants in the environment

10.1016/j.jep.2024.117892 209 ZhuQ.HanY.HeY.MengP.FuY.YangH.et al (2024b)