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Class precaution for MTC/MEN2 from preclinical thyroid C-cell observations

In a mouse model of myocardial ischemia, the ferroptosis inhibitor liproxstatin-1 (Lip-1) attenuated ischemia/reperfusion (I/R)-induced GPX4 depletion and reduced mitochondrial ROS production, accompanied by decreased VDAC1 expression and preservation of mitochondrial ultrastructural integrity