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In addition, SA can induce epigenetic changes, as its accumulation can modify the structure of chromatin

AGE generation is intricate and involves the Maillard reaction, the polyol pathway, the Namiki pathway, the Wolff pathway, the Hodge pathway, glycolysis and ketone body metabolism (Khalid et al

Pseudomonas exotoxin A (PE) is an extremely active monomelic protein (molecular weight 66 kD), secreted by Pseudomonas aeruginosa, which inhibits protein synthesis in eukaryotic cells through the inactivation of elongation factor 2 (EF-2) by catalyzing its ADP-ribosylation (catalyzing the transfer of the ADP ribosyl moiety of oxidized NAD onto EF-2)

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