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Well, that was before starting the B12 patch

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doi: 10.1038/nature25986 79 WeissJMDaviesLCKarwanMIlevaLOzakiMKChengRYet al

Disruptions in any of these systems can lead to the accumulation of misfolded, damaged, or aggregated mitochondrial proteins, ultimately causing cellular dysfunction and contributing to diseases such as mitochondrial myopathies and cardiomyopathies 10,11,12