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The 5-HT hypothesis primarily asserts that a decrease in the 5-HT level is a risk factor for depression

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TSH levels will then increase until around 13 hours post-dosage, where levels will stabilize

Integrin 51FAK/Src signaling is activated by alteration in the ECM composition, which in turn enhances the motility, while lymphocyte infiltration is restricted by the dense collagen network, adding another layer of immunosuppression (113)