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Significance was determined by unpaired two-tailed Students t -test ( a , c , d )

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Checking the soles of feet regularly will help identify early lesions, which are easier to treat

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The 2-OGDH assay contained 0.15-2 mM NAD + , 2 mM MgCl 2 , 1 mM DTT, 1 mM TPP, 0.025-1 mM CoA, 0.75-12 mM 2-oxo and 0.25-0.5 mg of protein

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