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Aging is associated with higher expression of metallothionein mRNA, reducing zinc bioavailability, and supplementation can restore zinc levels, enhancing NK cell cytotoxicity [210, 211]

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

Key Genes Associated with Mast Cell Activation Receptors and binding proteins: (FceR1A/B, ADGRE2, HRH1IL and IL33R) Receptors and binding proteins on the surface of mast cells may trigger histamine release