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however, there are important caveats: - Injection-site reactions: As with any injectable peptide, mild redness, swelling, or irritation at the injection site appear to be the most commonly reported side effects

Add too much water and your doses become impractically large volumes

Community sources variously attribute it to dose, to the DMSO carrier in transdermal use, or to vascular effects, with no way to confirm cause in self-reports