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GPX4 knockdown keratinocytes appeared to have a decreased capacity for cell adhesion, along with accumulating lipid peroxides and enhanced levels of various pro-inflammatory elements, including COX-2, 4-HNE, and prostaglandins (Sengupta et al., 2013)

Another study showed that certain cervical cancers did not express HPV oncogenes E6 and E7, and these were considered HPV-inactive tumors because they showed increased WNT/-catenin and sonic hedgehog signaling, decreased DNA methylation, enriched non-synonymous somatic mutations specifically targeting the TP53, ARID, WNT, and PI3K pathways

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39 Internal bracing treatment is another method for acute patellar tendon repair